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Testosterone e fattori di rischio cardiaco A dosi elevate, gli androgeni tendono ad aumentare i livelli di colesterolo LDL ("cattivo") e abbassare i livelli di colesterolo HDL. Questa è una delle cose che ha dato al testosterone una cattiva reputazione. Ma in altre circostanze, la situazione è molto diversa. Gli uomini che ricevono una terapia di deprivazione di androgeni per il cancro alla prostata riducono i loro livelli di testosterone quasi a zero e, quando ciò accade, i loro livelli di colesterolo aumentano. Anche all'interno dell'intervallo normale, gli uomini con i livelli più bassi di testosterone tendono ad avere i livelli più alti di colesterolo. E quando i medici della Mayo Clinic hanno esaminato 30 studi sulla terapia sostitutiva con testosterone, non hanno riscontrato alcun effetto complessivo del trattamento ormonale sui livelli di colesterolo, nel bene e nel male.
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